Multiplexed Detection of Anthrax-Related Toxin Genes
نویسندگان
چکیده
منابع مشابه
Identification of anthrax toxin genes in a Bacillus cereus associated with an illness resembling inhalation anthrax.
Bacillus anthracis is the etiologic agent of anthrax, an acute fatal disease among mammals. It was thought to differ from Bacillus cereus, an opportunistic pathogen and cause of food poisoning, by the presence of plasmids pXO1 and pXO2, which encode the lethal toxin complex and the poly-gamma-d-glutamic acid capsule, respectively. This work describes a non-B. anthracis isolate that possesses th...
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Anthrax spores can be aerosolized and dispersed as a bioweapon. Current postexposure treatments are inadequate at later stages of infection, when high levels of anthrax toxins are present. Anthrax toxins enter cells via two identified anthrax toxin receptors: tumor endothelial marker 8 (TEM8) and capillary morphogenesis protein 2 (CMG2). We hypothesized that host cells would be protected from a...
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ژورنال
عنوان ژورنال: The Journal of Molecular Diagnostics
سال: 2006
ISSN: 1525-1578
DOI: 10.2353/jmoldx.2006.050049